OsmoLax Clinical Evidence

The active ingredient in OsmoLax Relief, macrogol, has been clinically tested in multiple trials in adults and children with constipation.^1,2 These studies have shown that macrogol can assist in the effective treatment of constipation and is well tolerated by both adults and children.^1,2 Macrogol is generally more effective than lactulose.¹ The evidence has also shown that macrogol without salts (electrolytes), such as OsmoLax Relief, is as effective as those with added salts, but tends to be easier to take and so should be tried first.^1,2

One clinical study³ compared macrogol* without salts to macrogol with added salts. It was found that there was no difference in terms of effectiveness and side effects. 85% of patients in the group taking the macrogol product without salts were willing to continue treatment compared to 63% in the group taking the macrogol product with added salts, because of the salty taste of the latter.

In a study which compared macrogol without salts to macrogol with salts in children, 43% of children rated the taste of macrogol without salts as good or very good compared to only 2% in the group taking macrogol with added salts. There was no difficulty in giving macrogol without salts in 96% of children compared to 52% of children taking macrogol with added salts.⁴